What are the symptoms of the ATR-CM?

“ATTR-CMZ” is an abbreviation for “amyloid cardiomyopathy“This is a progressive medical condition caused by an accumulation of abnormal proteins in the heart which leads to an altered heart function. Symptoms of the FTR-CM often overlap other conditions, leading to a sub-diagnosis or delayed diagnosis.

Jump at the main dishes to remember.

Symptoms often associated with ATR-CM

ATTR-CM can cause a variety of symptoms, many of which can be vague. This makes it difficult to identify and obtain an early diagnosis for ATR-CM.

The symptoms for ATR-CM are:

• Abdominal bloating
• Chest congestion
• Quick heart rate
• Swelling with low content
• Palpitations
• Rigor
• Whistling and cough breathing, which worsens when it is elongated

In addition to the above symptoms, ATR-CM can also cause a variety of other health problems. Some of the most common conditions are:

• Carpal tunnel
• Numbness or tingling in the hands and feet
• Vertebral stenosis

Importance of early diagnosis

ATR-CM treatment does not heal the condition. Treatment may be able to slow down the development of diseases and minimize symptoms; Therefore, an early diagnosis is crucial to reduce the impact on the heart and the body.

Many ATR-CM symptoms are vague and non-specific, which means that they can occur in several other conditions. This can make the diagnosis difficult. It is important to inform your health care providers of family history of heart failure or ATR-CM.

A health professional will examine a patient’s medical history and current signs and symptoms. The diagnostic tools they can use to collect more information to make a diagnosis are:

• Electrocardiogram (ECG or EKG): An electrocardiogram looks at electrical conduction through the heart. It cannot provide a diagnosis but is used as a screening tool.
• Echocardiogram (echo):: An echocardiogram shows changes in the heart structure and the way the heart is able to pump blood.
• Magnetic heart magnetic resonance (MRI): This test gives a detailed view of the heart and shows the function and structure of the heart.
• Nuclear imaging:: Nuclear imaging can diagnose ATR-CM. The contrast material is injected with the patient. During the imaging test, the contrast binds to heart deposits caused by the ATT.
• Genetic tests: Once diagnosed with ATR-CM, a patient can undergo genetic tests, which can make the difference between hereditary and non-hereditary type of wild.

Attr-CM treatments

Available treatments include supporting therapies and more recent drugs that have proven to slow the progression of the disease.

Support therapies aim to reduce the volume of fluids (treatment with common heart failure) and reduce irregularities in heart rate (arrhythmias). These treatments can be:

The new drugs that can slow down the progression of the ATR-CM are:

• Attrup (Acoramidis)
• Vyndaqel (Tafamidis Meglumine)
• Vyndamax (Tafamidis)

Who is at risk for Artr-CM?

There are two types of ATR-CM, Hereditary and ATR-CM wild-type atr-CM.

The details on the hereditary anti-CM are:

• There is a genetic mutation (change) in the transthyretine gene which is transmitted by families.
• We find most often in the regions of Japan, Sweden, Portugal and Brazil, but the variants appear worldwide, including in people of Irish and African origin.
• Symptoms can start from 30 years old.
• The most common variant of ATR-CM in the United States affects 3% to 4% of African Americans.

The details on the wild-type attot are:

• Not caused by genetic changes
• Generally visible in older men
• Can also cause carpal tunnel syndrome, peripheral neuropathy (damaging the nerves outside the brain and spinal cord), lumbar column problems and even a breaking of the tendons of the forearms

Main to remember

• ATTR-CM is a rare and progressive condition that causes protein deposits in the heart, which makes the heart more difficult to pump effectively.
• This can lead to serious problems such as heart failure and symptoms are often vague or resemble other conditions.
• Because ATR-CM can be inherited, inform your health care provider if you have family history of heart failure or ATR-CM.