Svirk two in one have asthma attacks to the shot of young children

The inhalers who combine by providing immediate relief with a longer-term preventive effect are already recommended as a standard treatment of light asthma in people aged 12 and over in the United Kingdom, the United States and certain other countries. Today, a study of nearly 400 children in New Zealand has shown that these inhalers are more effective in young children, half reducing the number of asthms.

It remains to be seen whether the national and international directives will be modified on the basis of these results, explains Andy Bush, member of the team at the Imperial College, but the results are clearly cut. “Admittedly, if it was my child with asthma, I would have them on the combination,” he said.

The standard treatment of light asthma was formerly inhalers containing salbutamol, also known as alboterol, which relaxes muscles in the airways for 3 or 4 hours after use. These “lifter” inhalers were used if necessary.

If the lifting inhalers alone were insufficient, people received a second, separated inhaler containing a steroid which reduces immune inflammation which causes asthma. We thought that these “preventive” inhalers should be used regularly to have a protective effect, explains Bush. “The previous thing was that you had to take your inhaled steroids twice a day or they will not work,” says Bush. “Now it is clear that this is not necessarily the case.”

Large trials in adolescents and adults have shown that combined inhalers are more effective than this previous diet, even when used only if necessary. The steroid of these combined inhalers is called Budesonide and the lifter is formoterol, which works in the same way as salbutamol, but its effect lasts 12 hours.

There have been concerns about children using combined inhalers, in the sense that the steroid component could affect their growth, but the last study found no effect during the year of the trial. This involved 360 children assigned to random to receive either Budesonide-Formmoterol or Salbutamol for relief of symptoms on demand, with a stage up to twice a day of the Budesonide-Formloterol or Steroid Fluticasone, respectively, in the event of a serious asthma attack.

In other tests, the combined inhaler has reduced the overall consumption of steroids, explains Bush. Indeed, when people use them as needed, the dose of inhaled steroids they receive go up and descend in accordance with the severity of their symptoms. The reduction in the number of attacks also reduces the number of people who must be “spent” to a use twice a day of the combined inhaler, or who need a course in steroid pills.