Green labeling tool brands are progressing in protein chemistry

A new easy -to -use method to modify and label proteins quickly, precisely and at low cost was developed by chemists from the Australian National University (ANU).

The study was published in the journal Chem.

Protein marking is the process of fixing protein markers so that they can be observed under the microscope. It is an important tool that allows scientists to better record how proteins interact with other parts of the cell.

Dr. Elwy Abdelkader of Anu said that his team’s work is a big step forward in the field, because the methods currently available are often based on expensive chemicals and complex procedures, limiting their wider use.

“Using a method called expansion of the genetic code, we found a way to use cheap chemicals and easily available to program bacteria to make proteins with a special type of amino acid,” said Dr. Abdelkader.

“We can make sure that these amino acids are placed precisely where we want them in the protein, which allows us to” mark “the protein so that we can see it more easily under the microscope and follow it in living cells.

“We label the protein using a” ignition “fluorescence strategy, allowing a quick and clean generation of fluorescent markers exactly on the site where they are necessary.”

This could allow scientists to better detect new drugs and improve diagnoses, among other applications.

It is also a more respectful approach to the environment.

“Because we are counting on bacteria, we do not generate new chemical waste, and the process is more durable because toxic catalysts are avoided throughout,” said Dr. Abdelkader.