Complications of mononucleosis

People with weakened immune systems, including people with serious illnesses (such as HIV/AIDS) that weaken the immune system or people who take medications that suppress immunity (such as after an organ transplant), are generally at higher risk of developing complications from mono.

Additionally, some people may be more susceptible to developing illnesses related to monoinfection. “Some populations in Asia and Central America are at increased risk of cancer,” notes Dr. Balfour. (13,14) Although doctors aren’t sure what may be causing this elevated risk of developing mono-related cancers, one theory suggests that something in the environment could be to blame, according to Balfour. (3,9,10)

There is some evidence that genetics play a role in determining who is most likely to develop mono (among those infected with EBV), but whether or not there is a genetic explanation for who suffers from mono-related complications is a topic that requires further research.. (11,15,16,17)

Since some types of lymphoma are caused by EBV, researchers are also currently exploring this link to see if this link could help explain what makes some people more likely to develop EBV-related complications. (3.4)

If you have suffered from mono before and are experiencing similar symptoms again, consult your doctor to find out the possible cause of your condition. You may be suffering from a recurrence of mono, EBV-related complications, or another health problem with symptoms similar to mono, such as toxoplasmosis, cytomegalovirus infections, strep throat, or HIV. (2.18)