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Cartography The transition of the destiny of cells in space and time

Biotechnology nature, published online: July 16, 2025; DOI: 10.1038 / S41587-025-02704-X

The cells of a tissue influence each other by physical and chemical signals because they differentiate themselves from their final destinies and migrate into space. A new technique incorporates spatial transcriptomic data with the dynamics of RNA transcription and splicing through a whole fabric to model the directions of cellular differentiation and migration.

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