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Best Time to Take Echinacea for the Greatest Immune Boost

Key takeaways

  • The most effective time to take echinacea is immediately and frequently at the first signs of illness. Use it several times a day for up to 10 days.
  • For general well-being and prevention, take it for a few weeks during a high-risk season.
  • Echinacea is still being studied for its effects on colds and other respiratory tract infections. Continue to take other precautions, such as eating a healthy diet, getting enough sleep, and getting your annual flu shot.

Echinacea is used as a dietary supplement to help relieve symptoms of colds and other respiratory problems. The best time to take echinacea to get the most significant immune boost is immediately after noticing the first symptoms of an infection.

Best time for cold symptoms

The best time to get a maximum immune response against echinacea is to take it immediately at the first symptoms of a cold or flu. These may include a slight tickle in the throat, a runny nose, mild fatigue or discomfort.

Echinacea is not an antibiotic that directly kills pathogens. It stimulates the immune system, thus strengthening the body’s defense mechanisms. Taking the supplement early on can help activate the immune system to effectively fight off pathogens before they increase in number and take hold.

It’s important to note that while some studies show modest benefit in using echinacea to prevent or reduce cold symptoms, the research to date is mixed.

Best time for prevention during cold and flu season

The best time to begin a preventive dosing program is at the start of the high-risk cold and flu season (usually late fall or early winter).

Although it may seem beneficial to take an immune booster every day. However, continuous or long-term use of echinacea is generally not recommended. Constant stimulation of the immune system could eventually make it less responsive. Therefore, for year-round or seasonal prevention, a cyclical approach is recommended.

How does echinacea strengthen the immune system?

Echinacea flowers were initially used medicinally for respiratory tract infections, dental pain and snake bites. It is now commonly used to strengthen the immune system against respiratory tract infections.

Echinacea enhances immune system activity by stimulating various immune cells, including macrophages, neutrophils, and natural killer (NK) cells. The increased activity of these cells helps the body resist or fight infections.

Unlike other dietary supplements, when you take echinacea is one of the most critical factors in maximizing its immune-boosting benefits.

How often should I take echinacea?

Your dosing schedule for echinacea will vary depending on what you are using it for.

When using echinacea for acute respiratory infection:

  • Different product labels recommend a higher frequency for a short period of time.
  • Generally, take two to five times daily for up to seven to 14 days. In the short term, frequent doses produce an effective immune response.
  • For acute use, omitting doses may reduce effectiveness. Take the recommended doses regularly throughout the first few days of infection to help reduce the severity of symptoms.

For preventive use:

  • The dosage for the preventive cycle is generally lower and less frequent than for acute use, often once or twice daily, as indicated on the specific product label.
  • Take for a few weeks, then stop taking for a few more weeks. Repeat the cycle if necessary.
  • Continuous daily use for months is generally not recommended due to lack of long-term safety data.

Other ways to boost immunity

Although echinacea may provide benefits, it is essential to continue taking more evidence-based precautions to maintain a healthy immune system. This includes:

  • Have a balanced diet: Eating a variety of foods, including fruits and vegetables, provides several nutrients that help support a healthy immune system.
  • Get enough sleep: Poor sleep can negatively affect your immune system, making it harder to fight off infections.
  • Avoid alcohol: Drinking too much alcohol can weaken your immune system.
  • Get vaccinated against the flu: Receiving the seasonal flu vaccine can help reduce your chances of getting the flu or minimize symptoms if you do get it.
Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts in our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.
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  2. DailyMed. Label: Echinacea angustifolia pastille.

  3. Aucoin M, Cooley K, Saunders PR, et al. The effect of Echinacea spp. on the prevention or treatment of COVID-19 and other respiratory tract infections in humans: a rapid review. Advances in integrative medicine. 2020;7(4):203. doi:10.1016/j.aimed.2020.07.004

  4. David S, Cunningham R. Echinacea for the prevention and treatment of upper respiratory tract infections: a systematic review and meta-analysis. Ther Med supplement. 2019;44:18-26. doi:10.1016/j.ctim.2019.03.011

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  7. Manayi A, Vazirian M, Saeidnia S. Echinacea purpurea: Pharmacology, phytochemistry and analytical methods. Pharmacognosy reviews. 2015;9(17):63. doi:10.4103/0973-7847.156353

  8. Yale SH, Liu K. Echinacea purpurea therapy for the treatment of the common cold: a randomized, double-blind, placebo-controlled clinical trial. Arch Med Intern. 2004;164;(11):1237-1241. doi:10.1001/archinte.164.11.1237

  9. DailyMed. Label: Echinasyr-echinacea purpurea liquid.

  10. Centers for Disease Control and Prevention. Healthy habits: boost immunity.

  11. MedlinePlus. Flu vaccine.


By Ayesha Gulzar, PharmD

Ayesha Gulzar is a clinical pharmacist with interests in medical research, pharmacy practice, and drug therapy management. Dr Gulzar has worked in the field of medical communications, writing medical and clinical research for patients and healthcare professionals in the UK.

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