Treatment can consist of short -term therapies to be used during lighting rockets as well as long -term maintenance treatment. Treatment during a thrust aims to relieve symptoms and cause remission, or the end of the rocket.
Short-term anti-inflammatory drugs
During an enlightening rocket, short-term use of anti-inflammatory drugs, such as steroids, can help improve symptoms by reducing inflammation. Your doctor may prescribe them alongside other drugs.
- Corticosteroids Prednisone (Deltasone) and Budesonide (Entocort EC) can relieve symptoms and cause remission. But the use of long -term steroids can have serious side effects, so doctors generally recommend using them for short periods such as deck to other therapies.
Pain drugs
Pain medications will not shorten Crohn’s rocket, but they can reduce discomfort while you wait for other drugs to work. These include:
- Antispasmodic, such as dicyclomine (bentyl), which reduce cramps
- Acetaminophen, like tylenol, which relieves pain
Biologicals and other long -term treatments
- Anti-TNF agents Like infliximab (remicade) and adalimumab (humira) can shorten a rocket. These biological drugs reduce the immune response by targeting specific molecules and blocking the action of a protein known as a tumor necrosis factor, which causes inflammation.
- IL-12/23 inhibitors and IL-23 Like the Ustkinumab (Stelara) and Risankizumab (Skyrizi), are also biological drugs. They reduce inflammation by blocking proteins called interleukines, which play a role in activating the body’s immune response.
- Integrine blockers Reduce inflammation linked to Crohn by targeting precise molecules linked to the intestine. Vedolizumab (Entyvio), a biological medication, blocks the production of a type of integrine, a protein that allows cells causing inflammation to move blood in the tissues. It can also act as a maintenance medication between the lighting rockets.
- Like inhibitors, Which are non -organic synthetic molecules drugs can relieve symptoms faster than other non -steroid drugs. They reduce inflammation by blocking substances that lead to a defective immune response, and they can also prevent recurring rockets. In clinical trials, 58.8% felt symptom relief after two weeks. UPadacitinib (Rinvoq) was the first Jak inhibitor to obtain approval from the Food and Drug Administration of the United States (FDA) for having treated Crohn.
- Immunomodulators Like methotrexate (Trexall) and azathioprine (Imuran) are non -biological drugs that reduce inflammation by modifying the functioning of the immune system. But this can take 8 to 12 weeks to see an improvement after starting immunomodulators, so they are generally not used alone to treat acute rockets.
Will my medication change during a push?
A Crohn’s push does not necessarily mean that your drug diet has stopped working or that you will have to change it, explains Sobia Mujtaba, MD, MPH, gastroenterologist and assistant professor at the Emory University School of Medicine in Atlanta.
“Although this is one of the reasons for a rocket, [that] A certain medication has lost its effectiveness, other reasons include infections or if a drug should be optimized, “she said.
Medicines to avoid
Talk to your doctor before starting or changing medication or treatment, including over -the -counter medications, to make sure they will not worsen your symptoms or interact with other drugs.
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