NIH launches the consortium to reduce the risk of mortinity in the United States

Tuesday September 16, 2025

More than 60% of nearly 24,000 cases of close death per year remain unexplained.

The National Institutes of Health (NIH) have launched efforts to reduce the rate of avoidable mortincy in the United States. Investigators will develop tools, devices and other technologies that have the potential to allocate diagnostic and prevention efforts relevant to mortiniance, which occurs in 1 deliveries out of 160 in the United States, around 23,600 mortinities at 20 weeks or more gestation are reported each year.

More than 60% of the mortinity cases remain unexplained even after the exclusion of current causes, such as congenital anomalies, genetic factors and obstetric complications. The NIH will finance the Stillbirth Research Consortium for more than $ 37 million over five years, pending funds, with $ 750,000 in co -financing of the Ministry of Health and Social Services.

«Ce consortium fournira un programme de collaboration intégré pour soutenir les recherches de pointe afin d’identifier les causes profondes de la mortinaissance et d’informer les stratégies fondées sur des preuves pour lutter contre les risques de mortinaissance», a déclaré Alison Cernich, Ph.D., directrice par intérim des NIH des NIH Eunice Kennedy Shriver National Institute for Children’s Health and Human Development. “Too many families are unnecessarily confronted with the grief of mortinity.”

People who have known mortiniance are almost five times more likely to feel another complication associated with mortiniance or pregnancy. The rate of mortinity is considerably higher in blacks, American Indians and Alaska. About 40% of the mortanities that occur during work and birth are considered potentially preventable.

The Consortium of Mortinissance will be made up of four research centers and a data coordination center.

• The data coordination center At RTI International, Research Triangle, North Carolina, will facilitate the development and implementation of joint projects in research centers and ensure the rigor of study data and data sharing. The center will support common data elements, standard measurements and uniform data collection in research centers. The project will be led by Elizabeth McClure, Ph.D., and Carla Bann, Ph.D.
• Center of San Diego of the University of California for the Mortinissance Prevention Center Specialized in the identification of the causes of the placental dysfunction which underlie the restriction of fetal growth and contribute to the mortincy. The project is led by Mana Parast, MD, PH.D., director of the Perinatal Pathology Service; And Cynthia Gyamfi-Bannerman, MD, president and teacher of obstetrics, gynecology and reproductive services.
• Collaborative action for research to put an end to the Research Center on Mortinance (Cares) At Columbia University, New York, has expertise in electronic health files and artificial intelligence analysis to develop automated algorithms specifically for early identification of the risk of mortinity and to develop new, underlying placental dysfunction biomarkers to predict the obstruction. The project is led by Uma Reddy, MD, professor of obstetrics and gynecology; and Xiao XU, Ph.D., Associate Professor of Reproduction Sciences.
• The Research Center of the University of Utah Still -Birth has expertise in education, mourning / mental health and advocacy. The Center will estimate a decrease in fetal movement, the stratification of the risk of death based on a decrease in fetal movement and optimal strategies to manage it. This project is led by Robert Silver, MD, professor of obstetrics and gynecology, University of Utah Health Sciences Center, Salt Lake City.
• Nutrition and the results of reproductive injuries and misdeeds linked to mortinance (feed) (feed) Research center At Oregon Health & Science University, Portland, has expertise in the role of nutrition, chronic stress, cardiometabolic health and placental dysfunction to identify promising interventions aimed at reducing preventable mortinia. This project is led by Karen Gibbins, MD, assistant professor of obstetrics and gynecology; and Leslie Myatt, Ph.D., professor and director of perinatal research.

Project financing will be provided by UM2HD119552 UM2HD subsidies (Coordination Center); UG1HD119608; UG1HD119613; UG1HD119614; UG1HD119576.

For more information on mortiniance, visit this website of Eunice Kennedy Shriver National Child Health and Human Development.

On the Eunice Kennedy Shriver National Institute for Children’s Health and Human Development (NICHD): Nichd conducts research and training to understand human development, improve reproductive health, improve the lives of children and adolescents and optimize capacities for all. For more information, visit https://www.nichd.nih.gov.

On the National Institutes of Health (NIH): The NIH, the country’s medical research agency, includes 27 institutes and centers and is a component of the American department of health and social services. NIH is the main federal agency that leads and supports basic, clinical and translational medical research, and studies the causes, treatments and remedies for common and rare diseases. For more information on the NIH and its programs, visit www.nih.gov.

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